In-process rheometry as a PAT tool for hot melt extrusion
نویسندگان
چکیده
منابع مشابه
Hot-Melt Extrusion Technique: A Review
Hot-melt extrusion is one of the most widely applied processing technologies in the plastic, rubber and food industry. Today this technology has found its place in the array of pharmaceutical manufacturing operations. Melt extrusion process are currently applied in the pharmaceutical field for the manufacture of a variety of dosage forms and formulations such as granules, pellets, tablets, supp...
متن کاملHot-Melt Extrusion Technique: A Review
Hot-melt extrusion is one of the most widely applied processing technologies in the plastic, rubber and food industry. Today this technology has found its place in the array of pharmaceutical manufacturing operations. Melt extrusion process are currently applied in the pharmaceutical field for the manufacture of a variety of dosage forms and formulations such as granules, pellets, tablets, supp...
متن کاملHot Melt Extrusion Technique
Various approaches have been adopted to address this including preparation of solid dispersions and solid solutions. Hot-melt extrusion is an efficient technology for producing solid molecular dispersions with considerable advantages over solvent-based processes such as spray drying and co-precipitation. Hot-melt extrusion has been demonstrated to provide sustained, modified, and targeted drug ...
متن کاملInfluence of degassing on hot-melt extrusion process.
The present study aimed to evaluate the effect of degassing on an extrusion process, with respect to extrudate quality and drug release properties. Processed formulations were extruded with and without a degassing vent port at various locations along the barrel. All the experiments were performed under constant processing temperature, feeding rate, and screw speed. During the extrusion process,...
متن کاملhot-melt extrusion technique: a review
hot-melt extrusion is one of the most widely applied processing technologies in the plastic, rubber and food industry. today this technology has found its place in the array of pharmaceutical manufacturing operations. melt extrusion process are currently applied in the pharmaceutical field for the manufacture of a variety of dosage forms and formulations such as granules, pellets, tablets, supp...
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ژورنال
عنوان ژورنال: Drug Development and Industrial Pharmacy
سال: 2017
ISSN: 0363-9045,1520-5762
DOI: 10.1080/03639045.2017.1408641